MPP · Metabolic Performance Panel
Metabolic Performance Panel:
deeper data, better insights.
A comprehensive metabolomics assessment that evaluates 46 key metabolites across 7 core biochemical assessments to help uncover metabolic imbalances, support muscle health, and guide personalized treatment strategies.
MPP goes beyond traditional laboratory testing by examining metabolites that provide insight into how critical biochemical pathways are functioning.
From gut and amino acid metabolism to inflammation, methylation, cellular energy, and muscle health, MPP provides a more complete picture of metabolic function, giving providers actionable, data-driven information to support personalized care.
The 7 Core Assessments
1
Gut Assessment
2
Essential Amino Acids
3
Non-Essential Amino Acids
4
Inflammation & Oxidative Stress
5
B-Vitamin / Methylation Cofactors
6
Overall Cellular Energy Production
7
Muscle Assessment
46 key metabolites, organized into clinically meaningful areas.
Metabolic Performance + Muscle Health
A More Complete Picture
of metabolic function.
The MPP analyzes 46 key metabolites across 7 core assessments, providing insight into interconnected biochemical processes that influence health, performance, and longevity.
Unlike testing that focuses on individual biomarkers in isolation, MPP organizes metabolic information into clinically meaningful areas that help providers understand broader patterns of function.
7 Core Assessments
A comprehensive view across critical areas of metabolic health.
46 Key Metabolites
Advanced metabolomic analysis designed to provide deeper insight beyond traditional laboratory testing.
Dedicated Muscle Assessment
Evaluate key markers associated with muscle metabolism and protein turnover.
Personalized Insights
Translate complex metabolic data into clinically relevant information to support individualized interventions.
Why MPP Delivers More
Built to Go Beyond
a standard panel.
Dedicated Muscle Assessment
MPP includes a dedicated assessment of muscle metabolism and protein-turnover markers to provide insight into muscle health, recovery, and performance. This is particularly relevant for aging patients, active patients, patients focused on body composition, and those in weight-management programs.
7 Core Assessments
Rather than focusing on a single metabolic pathway, MPP evaluates seven clinically relevant areas that contribute to energy, detoxification, methylation, muscle health, and overall cellular function.
46 Key Metabolites
MPP evaluates 46 metabolic markers to provide a deeper view of biochemical function.
Actionable & Personalized
Results are organized to help providers identify meaningful metabolic patterns and use those insights alongside the patient’s clinical picture to guide nutrition, supplementation, lifestyle, and treatment strategies.
The 7 Core Assessments
Seven Areas.
One metabolic picture.
Assessment 1
Gut Assessment
Evaluate gastrointestinal & microbial metabolism
MPP evaluates metabolites associated with gastrointestinal health, microbial activity, dysbiosis-related patterns, and microbial byproducts.
Key markers include:
Benzoic Acid
Glutamine
Histidine
Lactic Acid
Pyruvic Acid
Assessment 2
Essential Amino Acids
Assess protein building blocks & utilization
Essential amino acids must be obtained through nutrition and play critical roles in protein synthesis, tissue repair, metabolism, and performance. MPP evaluates the intake, utilization, and metabolism of 8 essential amino acids.
Key markers include:
Histidine
Methionine
Threonine
Valine
and more
Assessment 3
Non-Essential Amino Acids
Evaluate amino acid metabolism
MPP evaluates 7 non-essential amino acids involved in neurotransmitter production, detoxification, nitrogen metabolism, and metabolic balance.
Key markers include:
Alanine
Asparagine
GABA
Glutamine
Tyrosine
Assessment 4
Inflammation & Oxidative Stress
Evaluate oxidative balance & cellular stress
MPP evaluates markers associated with oxidative stress, inflammation, and antioxidant capacity that can provide insight into processes affecting cellular health.
Key markers include:
3-Aminoisobutyric Acid
6-Sulfatoxymelatonin
8-OH-dG
Assessment 5
B-Vitamin / Methylation Cofactors
Evaluate methylation & related cofactors
Methylation and one-carbon metabolism influence detoxification, neurotransmitter synthesis, and DNA-related cellular processes. MPP evaluates methylation status and B-vitamin-related cofactors.
Key markers include:
Glycine
Methylmalonic Acid
S-Adenosylhomocysteine
Vanillylmandelic Acid
Assessment 6
Overall Cellular Energy Production
Understand the biochemistry behind energy
Cellular energy depends on coordinated metabolic pathways that convert nutrients into usable energy. MPP evaluates markers associated with mitochondrial function, nutrient utilization, and energy production.
Key markers include:
Carnitine
Succinic Acid
Assessment 7
Muscle Assessment
Dedicated insight into muscle metabolism
Muscle health becomes increasingly important in metabolic health, physical performance, healthy aging, and longevity.
MPP includes a dedicated Muscle Assessment evaluating muscle-metabolism and protein-turnover markers to provide additional insight into muscle health, recovery, and performance.
Key markers include:
1-Methyl-Histidine
3-Aminoisobutyric Acid
3-Methyl-Histidine
Beta-Alanine
Citrulline
Hydroxyproline
Proline
Why Muscle Assessment Matters
Muscle Is Central
to metabolic health and healthy aging.
Skeletal muscle plays an important role in physical function, glucose utilization, metabolic health, mobility, and healthy aging.
MPP’s dedicated Muscle Assessment adds another dimension to metabolomic testing by evaluating markers associated with muscle metabolism and protein turnover.
This can provide useful additional context for providers working with patients focused on:
Healthy aging and longevity
HRT/TRT optimization
Physical performance
Weight management
Body composition
Recovery
Energy
Why Metabolomics?
Look Beyond
traditional biomarkers.
Traditional laboratory testing measures important biomarkers such as glucose, cholesterol, hormones, and other circulating compounds.
Metabolomics provides a different perspective by evaluating small molecules produced through the body’s ongoing biochemical processes. These metabolites can provide information about areas such as:
Amino acid metabolism
Cellular energy
Methylation
Oxidative stress
Microbial metabolism
Nutrient utilization
Muscle metabolism
By evaluating patterns across multiple metabolites, MPP provides a functional view of metabolism that can complement conventional laboratory testing.
From 50+ Metabolites to Actionable Insight
Organized for
clinical use.
The value of MPP isn’t simply the number of metabolites measured. MPP organizes those metabolites into seven clinically relevant assessments, helping providers interpret individual results in the context of larger biochemical systems.
This approach is designed to make complex metabolomic information more useful in clinical practice.
Step 1
46 Metabolites
Step 2
7 Core Assessments
Step 3
Metabolic Patterns
Step 4
Personalized Insights
Step 5
Individualized Interventions
Clinical Applications
Ideal for a Wide Range
of patients.
Longevity & Healthy Aging
Evaluate metabolic, cellular-energy, nutritional, oxidative-stress, and muscle-related markers relevant to healthy aging strategies.
HRT / TRT Optimization
Add metabolic, nutritional, energy, and muscle-health context to individualized hormone optimization programs.
Active Lifestyle & Performance
Evaluate amino acid utilization, cellular energy, muscle metabolism, recovery-related markers, and metabolic performance.
Weight Management & GLP-1 Support
Provide additional insight into nutritional, metabolic, energy, and muscle-health patterns during medically supervised weight-management programs.
Fatigue & Energy Optimization
Evaluate metabolites associated with cellular energy production, nutrient utilization, amino acid metabolism, and related biochemical pathways.
Personalized Nutrition & Wellness
Use metabolomic information to provide additional context for individualized nutrition, supplementation, and lifestyle strategies.
Preventive Health
Provide a broader view of metabolic function that can complement conventional laboratory testing and clinical assessment.
Built for Personalized Medicine
Turn Metabolic Data
into individualized strategies.
Patients with similar symptoms, or even similar conventional laboratory results, can have very different metabolic patterns.
MPP gives providers another layer of biochemical information to consider when developing personalized care strategies.
Results can add context for
Nutrition
Supplementation
Lifestyle
Exercise & Recovery
Weight Management
Hormone Optimization
Healthy Aging & Longevity
MPP results should be interpreted alongside the patient’s medical history, symptoms, physical findings, medications, and other laboratory information.
Results Designed to Tell a Metabolic Story
A Complete Picture
of metabolic health.
MPP integrates seven critical metabolic assessments, including a dedicated Muscle Assessment, to help providers identify imbalances, evaluate metabolic performance, and develop personalized strategies.
Rather than presenting 46 disconnected measurements, the MPP report organizes findings into meaningful areas of metabolic function.
Step 1
Individual Metabolites
Step 2
7 Core Assessments
Step 3
Metabolic Patterns
Step 4
Personalized Clinical Context
Combine Metabolic Performance With Hormone Insight
MPP + Hormone360
= Total360.
Hormones and metabolism are interconnected. Total360 combines the comprehensive metabolic assessment of MPP with the hormone and metabolite analysis of Hormone360 to provide an integrated view of hormone metabolism and metabolic function.
For providers seeking expanded diurnal cortisol and cortisone assessment, Total360 Complete combines MPP with Hormone360 Complete.
MPP
Metabolic Performance + Muscle Health
+ Hormone360
Hormone Production + Metabolism
= Total360
Integrated Hormone + Metabolic Intelligence
Metabolic Performance + Muscle Health
Bring MPP
to your practice.
MPP evaluates 46 key metabolites across 7 core assessments, including a dedicated Muscle Assessment, to give providers a more comprehensive picture of metabolic function.
Deeper data. Better insights.