The most accurate and convenient form of testing


Physicians Lab exclusively uses LC/MS/MS Technology. This intricate instrumentation is unequivocally the finest instrument to quantitatively measure and distinguish analytes of similar structures, masses and binding behaviors, including steroid hormones.

Comparisons of RIA/ ELISA (methods routinely used to measure hormones) with GC-MS and LC/MS/MS have shown RIA and ELISA hormone results are much less accurate due to cross-reactivity between steroid hormones that can produce false elevations of up to 60%.


Faupel-Badger JM, Fuhrman BJ, Xu X, et al. Comparison of liquid chromatography-tandem mass spectrometry, RIA, and ELISA methods for measurement of urinary estrogens. Cancer Epidemiol Biomarkers Prev. 2010 Jan;19(1):292-300 

Frank Z. Stanczyk, Jennifer S. Lee and Richard J. Santen. Standardization of Steroid Hormone Assays:
Why, How, and When? Cancer Epidemiol Biomarkers Prev 2007;16:1713-1719.