Total360 · Hormone360 + MPP
Total360: A More Complete View
of the patient.
An integrated hormone and metabolic assessment combining Hormone360 with MPP, the Metabolic Performance Panel, to provide a broader view of hormone metabolism, metabolic function, nutritional needs, cellular energy, and biochemical pathways.
Hormones and metabolism don’t operate independently.
Total360 brings two of Physicians Lab’s advanced diagnostic platforms together to provide an integrated view of the biochemical systems influencing health and performance.
Hormone360
Hormone Metabolism & Adrenal Function
+ MPP
Metabolic Performance & Biochemical Pathways
= Total360
Integrated Hormone + Metabolic Intelligence
Two Powerful Assessments
Two Assessments.
One integrated view.
Traditional laboratory testing often evaluates individual biomarkers or physiological systems independently. Total360 is designed to look across systems.
By combining comprehensive hormone and metabolite testing with metabolomic assessment, Total360 gives providers information across hormone metabolism, cellular energy, amino acids, methylation, oxidative stress, nutritional needs, and related biochemical pathways.
The goal is to help providers move from isolated laboratory results toward a more connected understanding of the patient.
Why Measure Hormone Metabolites?
What Happens to a Hormone Can Be as Important
as how much is present.
Two patients can have similar hormone levels while metabolizing those hormones very differently.
Once hormones are produced, they are converted into downstream metabolites through multiple biochemical pathways. Evaluating those metabolites provides another layer of information that hormone levels alone may not reveal.
Hormone360 helps providers evaluate both sides of the equation:
Hormone Production
What is present?
Hormone Metabolism
What is the body doing with it?
Hormone360 + MPP
The Two Diagnostic Pillars
of Total360.
Hormone Metabolism & Adrenal Function
Hormone360
Hormone360 provides comprehensive assessment across:
-
Estrogens
-
Progesterone
-
Androgens
-
DHEA
-
Cortisol
-
Hormone metabolites
-
Metabolic ratios and pathways
Using a convenient first morning void, Hormone360 provides insight into hormone production and metabolism without requiring multiple collections throughout the day.
Metabolic Performance & Biochemical Pathways
MPP: Metabolic Performance Panel
MPP evaluates metabolites across critical biochemical pathways, including:
-
Amino acids
-
Cellular energy
-
Methylation & one-carbon metabolism
-
Oxidative stress & antioxidants
-
Nutritional needs
-
Metabolic pathways
Together, Hormone360 and MPP create a broader picture than either assessment provides independently.
What Total360 Evaluates
Seven Areas
across two platforms.
Hormone Metabolism
Comprehensive analysis of estrogens, progesterone, androgens, DHEA, and their metabolites.
Adrenal & Cortisol Health
Evaluate cortisol, cortisone, adrenal metabolites, and related pathways to provide additional context around adrenal hormone metabolism.
Metabolic Performance
Assess amino acids and biochemical markers associated with cellular energy and metabolic function.
Methylation & One-Carbon Metabolism
Evaluate methylation capacity and related biochemical markers, including pathways involving SAM, SAH, homocysteine, folate, B vitamins, and transsulfuration.
Oxidative Stress & Antioxidants
Evaluate markers associated with oxidative damage, glutathione metabolism, antioxidant status, and related biochemical pathways.
Nutritional Needs
Identify metabolic patterns that may provide insight into nutrient-related requirements and biochemical function.
Metabolic Ratios & Pathways
Evaluate advanced metabolic ratios and pathway relationships to provide deeper context around hormone and metabolic function.
Why Combine Hormone & Metabolic Testing?
The Systems
are connected.
Hormone physiology is influenced by, and can influence, metabolism.
Energy production, amino-acid availability, nutrient-related pathways, oxidative balance, methylation, and other biochemical processes provide important context when evaluating the patient as a whole. Total360 allows providers to examine these systems together.
Instead of asking only:
What are the patient’s hormone levels?
or:
What metabolic pathways appear imbalanced?
Total360 allows the provider to ask:
How do the patient’s hormone and metabolic patterns fit together?
More Data. Deeper Insights. Better Decisions.
One Platform.
A fuller diagnostic picture.
Total360 integrates hormone and metabolomic information to provide a more comprehensive diagnostic picture.
Comprehensive & Integrated
Evaluate hormone production, hormone metabolism, and metabolic pathways within one testing platform.
Actionable Clinical Insights
Organize complex laboratory findings into clinically meaningful categories and patterns.
Personalized Treatment Planning
Provide additional biochemical context to support individualized nutrition, supplementation, lifestyle, hormone, and other provider-directed interventions.
Health & Longevity Focus
Evaluate multiple systems relevant to metabolic performance and healthy aging.
Ideal For
Designed for Personalized
and longevity medicine.
Longevity & Healthy Aging
Evaluate hormone and metabolic systems together to provide a broad biochemical view for longevity-focused care.
HRT Optimization
Combine comprehensive hormone and metabolite assessment with metabolic information that can provide additional context during individualized hormone therapy.
Functional Medicine
Evaluate interconnected hormone and metabolic pathways rather than relying exclusively on isolated biomarkers.
Metabolic Optimization
Assess amino acids, cellular energy, nutrient-related pathways, oxidative stress, and other areas of metabolic function.
Fatigue & Energy Support
Evaluate biochemical pathways associated with cellular energy production and metabolic performance.
Personalized Nutrition
Use metabolic information to provide additional context when developing individualized nutrition and supplementation strategies.
Preventive Health
Provide a broad view of hormone and metabolic function that can complement conventional laboratory testing and clinical assessment.
Convenient At-Home Collection
Comprehensive Insight
without a trip to the lab.
Total360 combines:
Hormone360
First Morning Void
MPP
Metabolomic Assessment
Patients complete the required specimens at home and return them to Physicians Lab for laboratory analysis.
Results give providers both comprehensive hormone and metabolite information and metabolomic pathway insight.
Results Designed Around the Whole Picture
Integrated Hormone
+ metabolic intelligence.
Total360 is designed to help providers move beyond individual results and evaluate relationships across multiple systems.
Step 1
Hormones & Metabolites
Step 2
Metabolic Pathways
Step 3
Integrated Patterns
Step 4
Personalized Clinical Context
Need Expanded Diurnal Assessment?
Explore Total360
Complete.
Total360 Complete combines MPP with Hormone360 Complete’s 5-point urine collection, adding:
5-Point Diurnal Cortisol
5-Point Diurnal Cortisone
24-Hour Cortisol
24-Hour Cortisone
For providers seeking Physicians Lab’s broadest hormone, adrenal, and metabolic assessment, explore Total360 Complete.
Total360
First Morning Void + MPP
Total360 Complete
5-Point Urine Collection + MPP
A More Complete View of the Patient
Bring Total360
to your practice.
Total360 combines comprehensive hormone and metabolite testing with advanced metabolomic assessment to provide an integrated view of hormone metabolism, metabolic function, and biochemical pathways.
More data. Deeper insights. Better decisions.