• Physician’s Corner with Dr. Julie Kissel #1 November 26, 2018 High 4OHE1 4OHE1 is a catechol estrogen formed by aromatic hydroxylation of primary estrogens at either the C-2 or C-4 position.  4OHE1 can be oxidized to catechol estrogen quinones if it is not inactivated by COMT and/or sulfation, glucuronidation, etc. These catechol quinones can react with DNA to produce an excess of estrogen-DNA adducts with subsequent ...
  • Total Estrogen Load: Why Just Measuring Estradiol Isn’t Enough November 26, 2018 Total Estrogen and Precision Medicine: Treating Our Patients vs. Treating the Population Throughout the history of medicine, healthcare trends have evolved toward disease prevention instead of treating disease. Yet, the flood of lifestyle and dietary changes designed to avoid certain diseases seems to be more of a marketing strategy for food distributors, health clubs and supplement ...
  • New Laboratory November 21, 2018 We Are Officially in the New Lab Back in 2015, we started designing and developing our new laboratory. After repeated trial and error in the old lab, we knew EXACTLY what we were looking for. There was plenty of space, but the layout and instrumentation needed to be strategically planned. We wanted to expand our base ...