Urine Hormone & Metabolite Test
Hormone360: See More Than
Hormone Levels.
A comprehensive urine hormone and metabolite test designed to provide a more complete picture of hormone production, metabolism, and balance.
Hormone levels tell only part of the story. Hormone360 evaluates key hormones together with their downstream metabolites, helping healthcare providers understand not only hormone levels, but how those hormones are being metabolized.
The result is a deeper view of hormone physiology designed to support personalized hormone therapy, functional medicine, and longevity-focused care.
A Complete Hormone Picture
Go Beyond Individual
Hormone Levels.
Traditional hormone testing often focuses on a limited number of hormone measurements.
Hormone360 goes further by evaluating hormones, downstream metabolites, metabolic ratios, and pathways that provide additional context around hormone production and metabolism.
This expanded view helps providers move beyond isolated biomarkers to better understand the relationships between hormones and the pathways through which they are processed.
Complete Hormone Picture
A comprehensive assessment of hormones, metabolites, ratios, and pathways.
Clinically Actionable Insights
Laboratory information organized to help providers identify meaningful hormone and metabolic patterns.
Personalized Pathways Assessment
Evaluate how individual hormone metabolism pathways may differ from patient to patient.
Advanced Metabolite Analysis
Look beyond parent hormones to understand the downstream metabolites produced as hormones are processed.
Why Measure Hormone Metabolites?
What Happens to a Hormone Can Be as Important
as How Much Is Present.
Two patients can have similar hormone levels while metabolizing those hormones very differently.
Once hormones are produced, they are converted into downstream metabolites through multiple biochemical pathways. Evaluating those metabolites provides another layer of information that hormone levels alone may not reveal.
Hormone360 helps providers evaluate both sides of the equation:
Hormone Production
What is present?
Hormone Metabolism
What is the body doing with it?
Together, they provide a more comprehensive picture of hormone physiology.
What Hormone360 Measures
Five Clinically Relevant Areas.
One comprehensive report.
Hormone360 evaluates hormones, metabolites, metabolic ratios, and pathways across five clinically relevant areas.
Estrogens & Metabolism
9 markers
Estrone (E1)
Estradiol (E2)
Estriol (E3)
2-OH-E1
16α-OH-E1
4-OH-E1
2-Methoxy-E1
Estrogen Metabolites
Aromatase Activity
Progesterone & Metabolism
6 markers
5α-Pregnanediol
5β-Pregnanediol
Progesterone Metabolites
5α/5β Ratio
Progesterone Clearance
Postmenopausal PdG
Androgens & Metabolism
12 markers
Testosterone
DHT
Androsterone
Etiocholanolone
5α-Androstanediol
5β-Androstanediol
Androstenedione
DHEA
DHEA-S
Testosterone Metabolites
Testosterone/Metabolite Ratio
5α-Reductase Activity
Adrenal & Cortisol Metabolism
8 + 4 markers
Waking Cortisol
Waking Cortisone
DHEA & DHEA-S
Cortisol Metabolites (THF, THE, α-THF, THS)
11β-Hydroxy Metabolites
Total Cortisol Metabolites
Cortisol Clearance
11β-HSD II Ratio
Available with Hormone360 Complete 5-Point Collection
5-Point Diurnal Cortisol
5-Point Diurnal Cortisone
24-Hour Cortisol
24-Hour Cortisone
Metabolic Ratios & Pathways Assessment
7 markers
Total 17-Ketosteroids
Total 17-Hydroxysteroids
Cortisol Ratio
Anabolic/Catabolic Ratio
Estrogen Metabolism Ratios
Androgen Metabolism Ratios
Comprehensive Pathways Assessment
Convenient At-Home Collection
One Platform.
Two collection options.
Hormone360 gives providers two collection options depending on the level of hormone and adrenal assessment needed.
Advanced hormone testing doesn’t have to be complicated for the patient. Hormone360 offers convenient at-home urine collection, with the collection method determined by the level of assessment selected.
First Morning Void
Hormone360
One convenient urine collection.
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Estrogens, progesterone, and androgens with their metabolites
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Waking cortisol, cortisone, and adrenal metabolites
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Metabolic ratios and pathways assessment
5-Point Collection
Hormone360 Complete
Multiple collections throughout the day for expanded cortisol and cortisone assessment.
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Everything in Hormone360
-
5-point diurnal cortisol and cortisone
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24-hour cortisol and cortisone
Patients return their specimens to Physicians Lab for laboratory analysis, and results are delivered in a comprehensive report designed for provider interpretation.
Clinical Applications
Designed for Personalized
hormone care.
Menopause & Perimenopause Management
Gain a broader view of estrogen, progesterone, androgen, and hormone-metabolite patterns during hormonal transition.
Bioidentical Hormone Therapy Monitoring
Evaluate hormone levels together with downstream metabolism to provide additional context when monitoring individualized hormone therapy.
Adrenal Function & Stress Assessment
Evaluate cortisol, cortisone, adrenal metabolites, and related pathways, with expanded diurnal assessment available through Hormone360 Complete.
Men’s & Women’s Hormone Health
Assess sex hormones and their metabolites across both male and female hormone-health applications.
Functional & Integrative Medicine
Provide a more comprehensive view of interconnected hormone pathways for providers practicing personalized, functional, and integrative medicine.
Built for HRT Practices
Better Information
for individualized hormone therapy.
Hormone replacement therapy is highly individualized.
Patients receiving similar therapies may have different hormone levels, metabolite patterns, symptoms, and responses to treatment.
Hormone360 gives HRT providers a broader set of laboratory information by evaluating parent hormones together with downstream metabolites and metabolic pathways.
This additional context can support more informed, individualized clinical decision-making throughout the patient’s hormone-therapy journey.
Results Designed to Tell a Story
Clinical. Comprehensive.
Actionable.
A laboratory report should provide more than a page of numbers.
Hormone360 organizes hormone, metabolite, ratio, and pathway results to help providers recognize relationships across hormone production and metabolism.
The goal is to help move the provider from:
From
Individual Biomarkers
Through
Hormone & Metabolic Patterns
To
Clinical Context
Want an Even Broader View?
Add Metabolic Insight
with Total360.
Hormone health doesn’t operate independently from metabolism.
Total360 combines Hormone360 with the MPP (Metabolic Performance Panel) to provide additional insight into metabolic pathways, amino-acid metabolism, nutrient-related metabolism, methylation, cellular energy, oxidative stress, and other areas of metabolic function.
Hormone360
Hormone Production & Metabolism
+ MPP
Metabolic & Pathway Function
= Total360
A More Complete View of the Patient
Advanced Hormone Testing for Personalized Medicine
Bring Hormone360
to your practice.
Hormone360 provides healthcare providers with a comprehensive view of hormone production and metabolism, combining parent hormones, downstream metabolites, metabolic ratios, and pathway assessment in a clinically useful report.
Clinical. Comprehensive. Actionable.