Additional Testing
Targeted Testing.
Deeper clinical insight.
Focused laboratory assessments designed to provide additional insight into specific areas of patient health and physiology.
In addition to our comprehensive Hormone360, MPP, and Total360 testing platforms, Physicians Lab offers targeted testing options for providers who need deeper insight into specific physiological systems.
These focused panels can be used independently or alongside other laboratory testing based on the individual needs of the patient.
Available Now
Adrenal360
Targeted adrenal and cortisol assessment from a 5-point urine collection.
-
Diurnal cortisol and cortisone
-
24-hour cortisol and cortisone output
-
Adrenal hormone metabolism
As Physicians Lab expands its testing capabilities, additional specialized panels will be available here.
Adrenal360
A Deeper View
of adrenal function.
A comprehensive urine adrenal assessment that evaluates cortisol and cortisone throughout the day, along with adrenal hormone metabolites and key metabolic relationships.
Cortisol isn’t static. It follows a natural daily rhythm.
Adrenal360 uses a 5-point urine collection to provide insight into cortisol and cortisone patterns throughout the day while also evaluating adrenal hormone metabolism.
Rather than relying on a single cortisol measurement, Adrenal360 allows providers to examine both daily hormone patterns and underlying adrenal metabolism.

What Adrenal360 Measures
Five Views
of adrenal physiology.
5-Point Diurnal Cortisol
Evaluate cortisol at multiple points throughout the day to visualize the patient’s daily cortisol pattern.
5-Point Diurnal Cortisone
Evaluate cortisone alongside cortisol to provide additional context around glucocorticoid metabolism.
24-Hour Cortisol
Assess total cortisol output across the collection period.
24-Hour Cortisone
Assess total cortisone output across the collection period.
Adrenal & Cortisol Metabolism
Evaluate adrenal hormones, cortisol metabolites, clearance, and related metabolic pathways to provide a more complete picture than cortisol levels alone.
Key Adrenal360 Markers
The Same Adrenal Assessment
used in Hormone360 Complete.
Adrenal360 includes the Adrenal & Cortisol assessment used within Hormone360 Complete.
Adrenal & Cortisol
13 markers
5-Point Diurnal Cortisol
5-Point Diurnal Cortisone
24-Hour Cortisol
24-Hour Cortisone
Waking Cortisol
Waking Cortisone
DHEA
DHEA-S
Cortisol Metabolites (THF, THE, α-THF, THS)
11β-Hydroxy Metabolites
Total Cortisol Metabolites
Cortisol Clearance
11β-HSD II Ratio
Metabolic Ratios & Pathways Assessment
7 markers
Total 17-Ketosteroids
Total 17-Hydroxysteroids
Cortisol Ratio
Anabolic/Catabolic Ratio
Estrogen Metabolism Ratios
Androgen Metabolism Ratios
Comprehensive Pathways Assessment
Why Diurnal Testing?
See the Pattern,
not just the number.
Cortisol changes throughout the day. Evaluating multiple collection points provides information that a single measurement cannot show.
Adrenal360 helps providers visualize the patient’s daily cortisol and cortisone patterns while also evaluating total output and hormone metabolism.
Daily Pattern
How cortisol and cortisone change throughout the day.
Total Output
Overall cortisol and cortisone production across the collection period.
Metabolism
How cortisol and related adrenal hormones are being metabolized.
Together, these findings provide a more comprehensive view of adrenal physiology.
Convenient At-Home Collection
Five Timed Samples.
Collected at home.
Adrenal360 uses a convenient 5-point urine collection completed by the patient at home.
Timed specimens collected throughout the day allow Physicians Lab to evaluate cortisol and cortisone patterns across the patient’s daily cycle.
Samples are returned to Physicians Lab for laboratory analysis, with results organized into a comprehensive report designed for provider interpretation.
Clinical Applications
Designed for Targeted
adrenal assessment.
Adrenal360 can provide additional laboratory information for providers evaluating areas such as:
Adrenal Function & Stress Response
Fatigue & Energy
Sleep & Daily Rhythm
HRT Optimization
Functional & Integrative Medicine
Healthy Aging & Longevity
Adrenal360 results are intended to be interpreted by healthcare providers within the context of the patient’s clinical history, symptoms, medications, and other laboratory findings.
Need a Broader Hormone Assessment?
Explore Hormone360
Complete.
Adrenal360 focuses specifically on adrenal and cortisol assessment.
For providers who also want comprehensive evaluation of estrogens, progesterone, androgens, hormone metabolites, and metabolic ratios, Hormone360 Complete includes the full Adrenal360 assessment as part of Physicians Lab’s comprehensive hormone testing platform.
Adrenal360
Targeted Adrenal & Cortisol Assessment
Hormone360 Complete
Comprehensive Hormones + Metabolites + Adrenal360-Level Diurnal Assessment
Focused Testing. Actionable Insight.
Targeted Insight
when you need it.
Physicians Lab continues to expand its portfolio of specialized laboratory assessments designed to give providers targeted insight when comprehensive testing isn’t required.
Additional testing panels will be added as they become available.
