Additional Testing

Targeted Testing.
Deeper clinical insight.


Focused laboratory assessments designed to provide additional insight into specific areas of patient health and physiology.

In addition to our comprehensive Hormone360, MPP, and Total360 testing platforms, Physicians Lab offers targeted testing options for providers who need deeper insight into specific physiological systems.

These focused panels can be used independently or alongside other laboratory testing based on the individual needs of the patient.

Available Now

Adrenal360

Targeted adrenal and cortisol assessment from a 5-point urine collection.

  • Diurnal cortisol and cortisone

  • 24-hour cortisol and cortisone output

  • Adrenal hormone metabolism

As Physicians Lab expands its testing capabilities, additional specialized panels will be available here.

Adrenal360

A Deeper View
of adrenal function.

A comprehensive urine adrenal assessment that evaluates cortisol and cortisone throughout the day, along with adrenal hormone metabolites and key metabolic relationships.

Cortisol isn’t static. It follows a natural daily rhythm.

Adrenal360 uses a 5-point urine collection to provide insight into cortisol and cortisone patterns throughout the day while also evaluating adrenal hormone metabolism.

Rather than relying on a single cortisol measurement, Adrenal360 allows providers to examine both daily hormone patterns and underlying adrenal metabolism.

Illustrative chart of a daily cortisol and cortisone rhythm across five urine collection points, with levels highest in the morning and declining toward night. Not patient data.

What Adrenal360 Measures

Five Views
of adrenal physiology.

5-Point Diurnal Cortisol

Evaluate cortisol at multiple points throughout the day to visualize the patient’s daily cortisol pattern.

5-Point Diurnal Cortisone

Evaluate cortisone alongside cortisol to provide additional context around glucocorticoid metabolism.

24-Hour Cortisol

Assess total cortisol output across the collection period.

24-Hour Cortisone

Assess total cortisone output across the collection period.

Adrenal & Cortisol Metabolism

Evaluate adrenal hormones, cortisol metabolites, clearance, and related metabolic pathways to provide a more complete picture than cortisol levels alone.

Key Adrenal360 Markers

The Same Adrenal Assessment
used in Hormone360 Complete.

Adrenal360 includes the Adrenal & Cortisol assessment used within Hormone360 Complete.

Adrenal & Cortisol

13 markers

5-Point Diurnal Cortisol

5-Point Diurnal Cortisone

24-Hour Cortisol

24-Hour Cortisone

Waking Cortisol

Waking Cortisone

DHEA

DHEA-S

Cortisol Metabolites (THF, THE, α-THF, THS)

11β-Hydroxy Metabolites

Total Cortisol Metabolites

Cortisol Clearance

11β-HSD II Ratio

Metabolic Ratios & Pathways Assessment

7 markers

Total 17-Ketosteroids

Total 17-Hydroxysteroids

Cortisol Ratio

Anabolic/Catabolic Ratio

Estrogen Metabolism Ratios

Androgen Metabolism Ratios

Comprehensive Pathways Assessment

Why Diurnal Testing?

See the Pattern,
not just the number.

Cortisol changes throughout the day. Evaluating multiple collection points provides information that a single measurement cannot show.

Adrenal360 helps providers visualize the patient’s daily cortisol and cortisone patterns while also evaluating total output and hormone metabolism.

Daily Pattern

How cortisol and cortisone change throughout the day.

Total Output

Overall cortisol and cortisone production across the collection period.

Metabolism

How cortisol and related adrenal hormones are being metabolized.

Together, these findings provide a more comprehensive view of adrenal physiology.

Convenient At-Home Collection

Five Timed Samples.
Collected at home.

Adrenal360 uses a convenient 5-point urine collection completed by the patient at home.

Timed specimens collected throughout the day allow Physicians Lab to evaluate cortisol and cortisone patterns across the patient’s daily cycle.

Samples are returned to Physicians Lab for laboratory analysis, with results organized into a comprehensive report designed for provider interpretation.

Clinical Applications

Designed for Targeted
adrenal assessment.

Adrenal360 can provide additional laboratory information for providers evaluating areas such as:

Adrenal Function & Stress Response

Fatigue & Energy

Sleep & Daily Rhythm

HRT Optimization

Functional & Integrative Medicine

Healthy Aging & Longevity

Adrenal360 results are intended to be interpreted by healthcare providers within the context of the patient’s clinical history, symptoms, medications, and other laboratory findings.

Need a Broader Hormone Assessment?

Explore Hormone360
Complete.

Adrenal360 focuses specifically on adrenal and cortisol assessment.

For providers who also want comprehensive evaluation of estrogens, progesterone, androgens, hormone metabolites, and metabolic ratios, Hormone360 Complete includes the full Adrenal360 assessment as part of Physicians Lab’s comprehensive hormone testing platform.

Adrenal360

Targeted Adrenal & Cortisol Assessment

Hormone360 Complete

Comprehensive Hormones + Metabolites + Adrenal360-Level Diurnal Assessment

Focused Testing. Actionable Insight.

Targeted Insight
when you need it.

Physicians Lab continues to expand its portfolio of specialized laboratory assessments designed to give providers targeted insight when comprehensive testing isn’t required.

Additional testing panels will be added as they become available.