Total360 Complete · Hormone360 Complete + MPP
Total360 Complete: Our Most
Comprehensive Assessment.
Total360 Complete combines Hormone360 Complete’s 5-point hormone and adrenal assessment with MPP, the Metabolic Performance Panel, to provide Physicians Lab’s broadest integrated view of hormone metabolism, diurnal cortisol and cortisone patterns, metabolic function, nutritional needs, cellular energy, and biochemical pathways.
For providers seeking the deepest level of insight available within the Total360 platform, Total360 Complete brings comprehensive hormone, adrenal, and metabolomic assessment together.
Hormone360 Complete
Hormones + Metabolites + Diurnal Assessment
+ MPP
Metabolic Performance + Biochemical Pathways
= Total360 Complete
Comprehensive Hormone + Metabolic Intelligence
Builds on Total360
Everything in Total360.
Plus diurnal insight.
Total360 already combines comprehensive hormone and metabolite testing with advanced metabolomic assessment. Total360 Complete adds another dimension:
Time.
The Hormone360 Complete component uses a 5-point urine collection to evaluate cortisol and cortisone patterns throughout the day.
Providers receive the broad metabolic assessment of MPP together with comprehensive hormone and metabolite analysis and expanded information about daily adrenal patterns.
Five Collections. A Deeper Adrenal Picture.
Cortisol Is a Rhythm,
not just a number.
Cortisol changes throughout the day.
Total360 Complete evaluates cortisol and cortisone across multiple collection points, allowing providers to see the patient’s diurnal patterns rather than relying only on a single measurement.
5-Point Diurnal Cortisol
Visualize how cortisol changes throughout the day.
5-Point Diurnal Cortisone
Evaluate cortisone alongside cortisol to provide additional context around glucocorticoid metabolism.
24-Hour Cortisol
Assess total cortisol output across the collection period.
24-Hour Cortisone
Assess total cortisone output across the collection period.
Hormones + Daily Patterns + Metabolism
Three Layers
of diagnostic insight.
Total360 Complete brings three complementary layers of laboratory information together.
Layer 1
Hormone & Metabolite Assessment
Evaluate sex hormones, adrenal hormones, downstream metabolites, metabolic ratios, and hormone pathways.
Layer 2
Diurnal Cortisol & Cortisone Assessment
Evaluate how cortisol and cortisone patterns change throughout the day.
Layer 3
Metabolomic Assessment
Evaluate metabolites across pathways involved in amino-acid metabolism, cellular energy, methylation, oxidative stress, nutrient-related metabolism, detoxification, and related systems.
What Total360 Complete Measures
Hormones, Adrenal Patterns
and metabolic pathways.
Hormone Metabolism
Comprehensive analysis of estrogens, progesterone, androgens, DHEA, and downstream hormone metabolites.
Adrenal & Cortisol Health
Expanded adrenal assessment including:
5-Point Diurnal Cortisol
5-Point Diurnal Cortisone
24-Hour Cortisol
24-Hour Cortisone
Cortisol metabolites
Adrenal metabolites
Cortisol clearance
Related ratios and pathways
Metabolic Performance
Assess amino acids and biochemical pathways associated with cellular energy and metabolic function.
Methylation & One-Carbon Metabolism
Evaluate methylation capacity and related biochemical markers across interconnected one-carbon and transsulfuration pathways.
Oxidative Stress & Antioxidants
Evaluate markers associated with oxidative damage, glutathione metabolism, and antioxidant status.
Nutritional Needs
Identify metabolic patterns that may provide additional insight into nutrient-related requirements and biochemical function.
Metabolic Ratios & Pathways
Evaluate advanced ratios and pathway relationships across hormone and metabolic systems.
Why Combine Diurnal Hormone & Metabolomic Testing?
See More of the Patient’s Biochemistry
at the same time.
Hormone metabolism, adrenal physiology, nutrient status, energy metabolism, methylation, oxidative stress, and other metabolic pathways are interconnected.
Total360 Complete allows providers to examine these areas within one comprehensive testing platform.
The result is Physicians Lab’s broadest integrated assessment.
Not only
What hormones and metabolites are present
But also
How cortisol and cortisone change throughout the day
And
What is happening across important metabolic pathways
Total360 or Total360 Complete?
Choose the Level of Insight
your patient needs.
Total360
A comprehensive integrated hormone and metabolic assessment using the convenience of Hormone360’s first morning void plus MPP.
Total360 Complete
Physicians Lab’s broadest integrated assessment, adding 5-point diurnal cortisol and cortisone testing to the hormone, metabolite, and metabolomic information included in Total360.
More Data. Deeper Insights. Better Decisions.
Designed for Personalized
and longevity medicine.
Total360 Complete is particularly well suited for providers seeking broad biochemical information across multiple systems.
Longevity & Healthy Aging
A broad assessment of hormone, adrenal, and metabolic systems relevant to personalized longevity-focused care.
HRT Optimization
Combine hormone and metabolite assessment with diurnal cortisol and cortisone patterns and comprehensive metabolic information.
Functional Medicine
Evaluate multiple interconnected biochemical pathways within one integrated platform.
Metabolic Optimization
Assess cellular energy, amino acids, methylation, oxidative stress, nutritional needs, and metabolic pathways.
Fatigue & Energy Support
Evaluate adrenal patterns alongside biochemical pathways associated with energy production and metabolic performance.
Personalized Nutrition
Provide metabolic information that can support individualized nutrition and supplementation strategies.
Preventive Health
Complement conventional laboratory testing with a broader assessment of hormone and metabolic physiology.
Convenient At-Home Collection
Advanced Testing,
collected at home.
Total360 Complete brings advanced laboratory testing to the patient through convenient at-home specimen collection.
5-Point Urine Collection
Hormone360 Complete
Comprehensive hormone and metabolite testing plus diurnal cortisol and cortisone assessment.
Metabolomic Assessment
MPP
Insight across metabolites and critical biochemical pathways.
Patients return the specimens to Physicians Lab for laboratory analysis and comprehensive provider reporting.
Clinical. Comprehensive. Integrated.
Results Designed
to connect the dots.
Total360 Complete organizes information across hormone, adrenal, and metabolic systems to help providers see relationships that may be difficult to recognize when testing these systems independently.
Step 1
Hormone Production & Metabolism
Step 2
Diurnal Cortisol & Cortisone
Step 3
Metabolic & Biochemical Pathways
Step 4
Integrated Patterns
Step 5
Personalized Clinical Context
Hormone360 Complete + MPP = Total360 Complete
Bring Total360 Complete
to your practice.
Total360 Complete brings together Physicians Lab’s most comprehensive hormone, adrenal, and metabolomic testing to provide an integrated picture of hormone metabolism, daily cortisol and cortisone patterns, metabolic performance, nutritional needs, and biochemical pathways.
More data. Deeper insights. Better decisions.