A Liquid Chromatography-Mass Spectrometry Method for the Simultaneous Measurement of Fifteen Urinary Estrogens and Estrogen Metabolites: Assay Reproducibility and Inter-individual Variability
Source: Cancer Epidemiol Biomarkers Prev. 2008 December ; 17(12): 3411–3418. doi: 10.1158/1055-9965.EPI-08-0355. RT Falk1, X Xu2, L Keefer3, TD Veenstra2, and RG Ziegler1 Abstract Background—Accurate, reproducible, and sensitive measurements of endogenous estrogen exposure and individual patterns of estrogen metabolism are needed for etiologic studies of breast cancer. We have developed a high performance liquid chromatography-tandem mass spectrometry…