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Common Clinical Findings Uncovered Through Urinary Metabolite Testing

By: Stacy Hinz, MS There are many reasons to use 24-hour comprehensive urinary testing in assessing hormones and metabolites in the steroidogenic pathways, but most practitioners choose comprehensive urinary hormone testing for the following reasons: Urinary hormones are a direct measurement of the active free hormone available to the tissue receptors. In serum, the amount…

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Calculations to Diagnosis: The Artificial Intelligence Shift That’s Already Happening

Co-authored by Clifford Morris, PhD and Thomas Kent Paradigm of Artificial Intelligence Technology moves only in one direction—forward. In general, the observation of this fact is welcome. After all, the ability to develop and apply technology is a defining aspect of our species. This fact becomes unwelcome when outcome-driven industries trade their lots for technological…

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Explaining to Patients the Importance of Testing Estrogen Metabolism and Strategies

By: Mari Salazar, PA, MMS Patient education. We all know it’s important, we’d like to do more of it, but it’s time consuming and, frankly, some of us aren’t good at it. Some patients like a lot of it, while some patients feel overwhelmed and are turned off. And when you add to this the…

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Hormonal and Dietary Approaches to Alzheimer’s Disease Prevention

By: Clifford Morris, Ph.D. Chief Chemist and Research Scientist Introduction The largest failure of the biomedical research enterprise over the past 50 years has been its inability to adequately address Alzheimer’s disease. There are currently four FDA-approved medications for the relief of Alzheimer’s symptoms; three of which are acetylcholine esterase inhibitors, and the other is…

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24-Hour Urinary Testing: The Difference Between Sick and Well

By: Catherine Chua, DO, FAAFP, FMNM, CPE (Certified Physician Executive) Chief Medical OfficerDavis Health SystemElkins, WV While attending courses during my Fellowship training, I distinctly remember an esteemed colleague asking the audience, “How many of you think that women develop a Prozac deficiency when they turn 35?”  We were all somewhat stunned at the question,…

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New Patient Report: The Latest & Greatest

By: Stacy Hinz, MSDirector of Clinical Education Physicians Lab envisions bringing the highest level of clinical relevance and education to practitioners who see the value in personalizing medicine to each patient. We currently have a large number of educational videos, training documents, and one-on-one training opportunities. This year, we continue to focus on superior education…

Reliability of Saliva Hormone Tests

J Am Pharm Assoc. 2003;43:724–6. – Jolena Hagen, Nicolette Gott, and Donald R. Miller Recent reports concerning the safety of hormone replacement therapy (HRT) have led many women to seek alternative ways to treat menopausal symptoms. A new alternative that has become very popular is bioidentical HRT.  This therapy is often based on the results…

A Liquid Chromatography-Mass Spectrometry Method for the Simultaneous Measurement of Fifteen Urinary Estrogens and Estrogen Metabolites: Assay Reproducibility and Inter-individual Variability

Source: Cancer Epidemiol Biomarkers Prev. 2008 December ; 17(12): 3411–3418. doi: 10.1158/1055-9965.EPI-08-0355.  RT Falk1, X Xu2, L Keefer3, TD Veenstra2, and RG Ziegler1 Abstract Background—Accurate, reproducible, and sensitive measurements of endogenous estrogen exposure and individual patterns of estrogen metabolism are needed for etiologic studies of breast cancer. We have developed a high performance liquid chromatography-tandem mass spectrometry…