By: Stacy Hinz, MS There are many reasons to use 24-hour comprehensive urinary testing in assessing hormones and metabolites in the steroidogenic pathways, but most practitioners choose comprehensive urinary hormone testing for the following reasons: Urinary hormones are a direct measurement of the active free hormone available to the tissue receptors. In serum, the amount…
Co-authored by Clifford Morris, PhD and Thomas Kent Paradigm of Artificial Intelligence Technology moves only in one direction—forward. In general, the observation of this fact is welcome. After all, the ability to develop and apply technology is a defining aspect of our species. This fact becomes unwelcome when outcome-driven industries trade their lots for technological…
By: Mari Salazar, PA, MMS Patient education. We all know it’s important, we’d like to do more of it, but it’s time consuming and, frankly, some of us aren’t good at it. Some patients like a lot of it, while some patients feel overwhelmed and are turned off. And when you add to this the…
By: Clifford Morris, Ph.D. Chief Chemist and Research Scientist Introduction The largest failure of the biomedical research enterprise over the past 50 years has been its inability to adequately address Alzheimer’s disease. There are currently four FDA-approved medications for the relief of Alzheimer’s symptoms; three of which are acetylcholine esterase inhibitors, and the other is…
By: Catherine Chua, DO, FAAFP, FMNM, CPE (Certified Physician Executive) Chief Medical OfficerDavis Health SystemElkins, WV While attending courses during my Fellowship training, I distinctly remember an esteemed colleague asking the audience, “How many of you think that women develop a Prozac deficiency when they turn 35?” We were all somewhat stunned at the question,…
By: Stacy Hinz, MSDirector of Clinical Education Physicians Lab envisions bringing the highest level of clinical relevance and education to practitioners who see the value in personalizing medicine to each patient. We currently have a large number of educational videos, training documents, and one-on-one training opportunities. This year, we continue to focus on superior education…
Trouble With The Curve: It’s Not Just a Movie A practitioner’s approach to the cortisol curve By: Benita Phillips, D.O. How many times have you looked at a patient’s cortisol curve and said to yourself: “That just doesn’t make sense!” And you think: “This person should feel fine…” Or the contrary: “How does this…
Short Communication: Implications of Flaxseed on Urinary Hormone Testing By: Clifford Morris, Ph.D. Cand., Chief Chemist and Research Scientist Flaxseed and Phytoestrogens Flaxseed is a powerful plant that has achieved massive interest, yet much of what people know about flaxseed is simply misunderstood. Flaxseed is a popular dietary source of lignans, which are a type…
The Role of CBD in Maintaining the Endocannabinoid System and HPA Axis Balance By: Clifford Morris, Ph.D. Cand., Chief Chemist and Research Scientist In this article, we will shed light on the nebulous topic of cannabidiol (CBD), including the effects of CBD on the Hypothalamic-Pituitary-Adrenal (HPA) axis, stress, and inflammation. The legalization of medical cannabis…
High 4OHE1 4OHE1 is a catechol estrogen formed by aromatic hydroxylation of primary estrogens at either the C-2 or C-4 position. 4OHE1 can be oxidized to catechol estrogen quinones if it is not inactivated by COMT and/or sulfation, glucuronidation, etc. These catechol quinones can react with DNA to produce an excess of estrogen-DNA adducts with…